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Product Name: Sitagliptin Phosphate 50 mg + Metformin Hydrochloride 500 mg

Regulate Blood Sugar with JANUPTIN 50 M 500

Product Description:JANUPTIN 50 M 500

Our Sitagliptin Phosphate 50 mg + Metformin Hydrochloride 500 mg is a combination medication designed to help manage type 2 diabetes mellitus in adult patients. This product is formulated to provide a synergistic effect by combining two different classes of antidiabetic drugs, sitagliptin and metformin, in a single tablet.

Active Ingredients:JANUPTIN 50 M 500
1. Sitagliptin Phosphate – 50 mg
2. Metformin Hydrochloride – 500 mg

Indications:JANUPTIN 50 M 500
Sitagliptin Phosphate and Metformin Hydrochloride combination is indicated for the treatment of type 2 diabetes mellitus in adults. This medication helps to control blood sugar levels and improve glycemic control when diet and exercise alone are not sufficient.

Mode of Action:JANUPTIN 50 M 500
– Sitagliptin Phosphate: This active ingredient belongs to the dipeptidyl peptidase-4 (DPP-4) inhibitor class. It works by inhibiting the enzyme DPP-4, which in turn increases the levels of active incretin hormones, such as GLP-1 and GIP. These hormones stimulate insulin release and reduce glucagon secretion, leading to better blood glucose regulation.

– Metformin Hydrochloride: Metformin is a biguanide and works by reducing glucose production in the liver and increasing insulin sensitivity in peripheral tissues, such as muscle and fat cells. It also improves glucose uptake by cells, further aiding in blood sugar control.

Dosage and Administration:JANUPTIN 50 M 500
– The recommended dosage is one tablet of Sitagliptin Phosphate 50 mg + Metformin Hydrochloride 500 mg orally twice daily.
– It is advisable to take the tablet with meals to reduce the risk of gastrointestinal side effects associated with metformin.

Do not use Sitagliptin Phosphate 50 mg + Metformin Hydrochloride 500 mg in the following conditions:
– Patients diagnosed with type 1 diabetes or those who have a history of diabetic ketoacidosis.
– Patients with severe renal impairment or end-stage renal disease (eGFR < 30 mL/min/1.73 m²).
– Patients with a known hypersensitivity to sitagliptin, metformin, or any other component of the product.

Precautions and Warnings:JANUPTIN 50 M 500
– Regular monitoring of renal function is recommended, especially in elderly patients and those with known renal impairment.
– This medication should be temporarily discontinued before certain radiologic studies involving intravascular administration of iodinated contrast materials to reduce the risk of acute kidney injury.
– Use with caution in patients with a history of pancreatitis or risk factors for pancreatitis.
– It is essential to inform healthcare providers about all the medications you are taking to prevent potential drug interactions. This includes prescription medications, over-the-counter drugs, herbal supplements, and any other substances you may be using. Being transparent about your current medication regimen will help healthcare professionals make informed decisions and ensure your safety while using Sitagliptin Phosphate 50 mg + Metformin Hydrochloride 500 mg or any other medications.

Adverse Effects:JANUPTIN 50 M 500
Common side effects may include nausea, diarrhea, abdominal discomfort, and headache. If you experience any unusual or severe symptoms while taking Sitagliptin Phosphate 50 mg + Metformin Hydrochloride 500 mg or any other medication, it is important to seek medical attention immediately. Promptly reporting any unexpected or serious side effects to healthcare professionals will allow them to assess your condition and provide appropriate medical care to ensure your well-being. Your health and safety are of utmost importance, and timely communication with healthcare providers can make a significant difference in managing any potential health concerns.

Storage:JANUPTIN 50 M 500
-Store Sitagliptin Phosphate 50 mg + Metformin Hydrochloride 500 mg at room temperature, and ensure it is kept away from moisture and heat. Additionally, be sure to store the medication in a place that is out of reach of children and pets. Proper storage helps maintain the integrity and effectiveness of the product and prevents any accidental ingestion by children or animals, ensuring the safety and efficacy of the medication for its intended use.

Note: This product catalogue provides general information about Sitagliptin Phosphate 50 mg + Metformin Hydrochloride 500 mg. Please consult your healthcare professional for detailed prescribing information and personalized advice.


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